Asymmetric assembly of 2-oxindole and α-angelica lactone units to construct vicinal quaternary chiral centers.
نویسندگان
چکیده
The first organocatalytic asymmetric assembly of Morita-Baylis-Hillman carbonates of isatins and α-angelica lactone has been studied, affording multifunctional products containing two valuable pharmacophores and vicinal quaternary chiral centers in high stereoselectivity (up to 92% ee, dr >95:5).
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 18 شماره
صفحات -
تاریخ انتشار 2012